Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft. Werde Teil von Roche, wo jede Stimme zählt.
Die Position
In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
At the intersection of science and innovation, pRED’s Pharmaceutical Sciences (PS) organization enables the discovery and development of safe and effective therapeutics at optimal doses in relevant populations with a vision to power translation, continuously improve the accuracy of our predictions and accelerate the development of tomorrow's medicines. By seamlessly integrating our three core pillars—Translational Safety, Translational Pharmacology, and Biomarkers—we drive End to End asset development across the entire value chain, from target assessment to on-market support. Our mission is to continuously improve predictive accuracy, optimize dosing strategies for the right patient populations, and accelerate the development of tomorrow's safe and effective therapeutics.
The Opportunity
Serving as a technical expert within the ADME chapter of Pharmaceutical Sciences (PS). The primary objective is to drive the discovery portfolio forward by providing high-quality, actionable in vitro bioanalytical data that informs drug candidate selection.
- Mass Spectrometry& HPLC Operation: Independently develop and validate robust bioanalytical methods using HPLC and triple quad (Sciex) or high-resolution (e.g. Orbitrap/Thermo) mass spectrometry.
- Multi-Modality Quantification: Lead the quantification and rigorous data analysis for a diverse portfolio including small molecules, peptides, and oligonucleotides.
- Digital Transformation: Design and implement workflow automation and digitalization initiatives to streamline laboratory data flow and experimental execution.
- Strategic Throughput Optimization: Continuously evaluate and optimize the BA strategy to specifically increase sample throughput and reduce manual data analysis time.
- Large Molecule Support: Provide technical expertise for the quantification of large molecules as required by the pRED discovery pipeline.
- Optimize BA strategy to increase throughput and automation of data analysis
- Cross-Functional Collaboration: Partner with the ADME team to interpret bioanalytical results and influence project progression.
- Roche Leadership Framework: Demonstrate a Creative Mindset and VACC (Visionary, Architect, Catalyst, Coach) principles in all interactions, even as an individual contributor.
Who You Are
- An MSc or PhD degree in bioanalysis, biochemistry or a related relevant discipline, paired with proven practical experience, ideally within an industrial setting.
- Take full ownership of the quality, accuracy, and timely delivery of in vitro bioanalytical data supporting discovery projects.
- Exercise authority to permanently optimize laboratory processes, ensuring they meet evolving quality and efficiency standards.
- Act as a primary technical point of contact for internal stakeholders, utilizing high-level communication and collaboration skills to align on project needs.
- Apply economic and entrepreneurial thinking to prioritize tasks and manage laboratory resources effectively within the ADME department
- Permanently optimizes processes in order to increase quality and efficiency standards.
At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.
Wer wir sind
Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.
Gemeinsam können wir eine gesündere Zukunft gestalten.
Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.
