Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.
We are seeking a highly motivated
Bioanalytical Scientist / Research Associate to support the development and execution of
bioanalytical strategies for large molecule therapeutics. The successful candidate will play a key role in establishing, developing, qualifying, validating, troubleshooting, and overseeing immunoassays used to support preclinical and clinical studies.
This position combines
hands-on laboratory work with external study coordination, requiring close collaboration with contract research organizations (CROs), project teams, and cross-functional stakeholders. The ideal candidate is scientifically rigorous, highly organized, and experienced in bioanalytical support for complex biologic modalities.
Bioanalytical Assay Development & Validation
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Design, develop, optimize, qualify, and validate bioanalytical methods for large molecule therapeutics.
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Establish, develop, and perform immunoassays, including ligand-binding assays (LBAs) such as ELISA, MSD/ECL, Gyrolab, and related platforms.
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Lead assay troubleshooting, root-cause investigations, and implementation of corrective actions.
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Generate robust bioanalytical data to support pharmacokinetic (PK), immunogenicity (ADA/NAb), and biomarker assessments.
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Ensure assays are fit-for-purpose and compliant with applicable regulatory guidance and industry best practices.
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Contribute to the scientific interpretation of bioanalytical data and preparation of study reports.
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Analyze, document, and communicate experimental results clearly and accurately.
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Maintain relevant laboratory documentation, assay procedures, and validation records.
CRO Management & External Collaboration
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Serve as the bioanalytical point of contact for external CRO partners.
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Coordinate assay transfer, method development, qualification, validation, and sample analysis activities conducted by CROs.
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Review study protocols, validation plans, data packages, and final reports.
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Monitor study timelines, deliverables, data quality, and regulatory compliance.
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Collaborate with internal project teams to ensure timely delivery of bioanalytical support across programs.
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Provide scientific oversight of outsourced bioanalytical activities and contribute to vendor selection and performance evaluation.
Education & Experience
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MSc in Biology, Biochemistry, Biotechnology, Pharmaceutical Sciences, Immunology, or a related field with relevant industry experience; or PhD in a relevant scientific discipline.
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3+ years (Research Associate) or 5+ years (Scientist) of relevant experience in bioanalysis of large molecule therapeutics within biotechnology, pharmaceutical, or contract research laboratory environments.
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Proven hands-on experience developing, qualifying, validating, overseeing, and troubleshooting immunoassays.
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Experience supporting pharmacokinetic, immunogenicity, and biomarker bioanalysis programs.
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Experience managing outsourced bioanalytical activities and working effectively with CROs.
Technical Skills-
Strong expertise in ligand-binding assays and immunoassay platforms (ELISA, MSD/ECL, Gyrolab, or equivalent).
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Familiarity with regulatory expectations and guidance for bioanalytical method validation.
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Strong data analysis, interpretation, and scientific reporting skills.
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Experience working in GxP-regulated environments is an advantage.
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Experience with MS applications for complex therapeutic modalities is considered a plus
Personal Attributes-
Hands-on, proactive, and solution-oriented scientist.
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Strong troubleshooting and problem-solving capabilities.
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Excellent organizational and project coordination skills.
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Strong communication skills and the ability to collaborate effectively across internal and external teams.
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Capable of managing multiple priorities in a dynamic environment.
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People: We are an international and diverse team with talented and passionate people.
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Creativity: We offer an innovative and creative environment.
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Development: We support the individual development of our employees.
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Fun: From time-to-time we organise cool off-site summer and winter team events.
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Offices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
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Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
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Flexible Working: We support flexible working as appropriate.
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Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
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Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
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Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
Please note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement.